THE END-USER FOCUSSED WAY TO DEVELOP MEDICINES
The image below highlights the principles. Instead of the current three step process of discovery, development and final production, we move to a two-step process – prototyping and final production:
Prototyping is used in every other industry except medicines. In aviation, it’s wind tunnels and flight simulators. There’s no appetite to do the same for medicines.
We want to change that with STEM – Science, Technology, Engineering and Maths. At the core of STEM is integration of all the skills required to bring products to market. This is the missing ingredient we want to put back in the pot.
WHAT ARE THE UNDERPINNING PRINCIPLES?
People treated as individuals with prevention, diagnostic and therapy needs.
If medicine needed, healthcare professionals (HCPs) involved at the start.
Involve all the professions needed to develop a medicine AT THE BEGINNING.
Remove the brick-wall between discovery and development, to make it one group titled ‘DESIGN’.
Group develops prototypes to be tested for suitability for patients and HCPs.
Supply chains should be designed strategically, making them simple and streamlined.
HOW DO WE KNOW IT WILL WORK?
The medicines’ industry wasn’t always like this. In 1950, the then head of one of the world’s largest pharmaceutical companies, George W Merck, famously said “We try never to forget that medicine is for the people. It is not for the profits. The profits follow, and if we have remembered that, they have never failed to appear. The better we have remembered it, the larger they have been!” We rest our case.